Igeragezwa ry’amavuriro ryatangiriye muri Repubulika Iharanira Demokarasi ya Kongo (DRC) kugira ngo harebwe akamaro k’imiti ya virusi ya tecovirimat (izwi kandi ku izina rya TPOXX) ku bantu bakuru ndetse n’abana bafite monkeypox.Ikigeragezo kizasuzuma umutekano w’ibiyobyabwenge nubushobozi bwacyo bwo kugabanya ibimenyetso bya monkeypox no gukumira ingaruka zikomeye zirimo urupfu.Ku bufatanye bwa guverinoma ya PALM, Ikigo cy’igihugu gishinzwe allergie n’indwara zandura (NIAID), igice cy’ikigo cy’igihugu cy’ubuzima, n’ikigo cy’igihugu gishinzwe ubushakashatsi ku binyabuzima (INRB) cya Repubulika Iharanira Demokarasi ya Kongo bafatanya kuyobora ubushakashatsi..Ibigo bifatanya birimo Ikigo cyo muri Amerika gishinzwe kurwanya no gukumira indwara (CDC), Ikigo cya Antwerp gishinzwe ubuvuzi bw’ubushyuhe, Umuryango mpuzamahanga w’ubuzima (ALIMA), n’umuryango w’ubuzima ku isi (OMS).
Yakozwe na sosiyete ikora imiti SIGA Technologies, Inc. (New York), TPOXX ni FDA yemerewe ibicurane.Uyu muti uhagarika ikwirakwizwa rya virusi mu mubiri, ukirinda kurekura virusi ziva mu ngirabuzimafatizo z'umubiri.Uyu muti wibasira poroteyine iboneka muri virusi ya virusi ndetse na virusi ya monkeypox.
Umuyobozi wa NIAID, Anthony S. Fauci, MD, yagize ati: "Monkeypox itera umutwaro ukomeye w'indwara n'urupfu mu bana ndetse n'abantu bakuru muri Repubulika Iharanira Demokarasi ya Kongo, kandi hakenewe uburyo bunoze bwo kuvura."Ingaruka zo kuvura monkeypox.Ndashaka gushimira abafatanyabikorwa bacu ba siyanse baturutse muri DRC n’Abanyekongo ku bufatanye bakomeje guteza imbere ubu bushakashatsi bw’ubuvuzi.”
Virusi ya Monkeypox yateje indwara rimwe na rimwe kuva mu myaka ya za 70, cyane cyane mu turere tw’amashyamba yo muri Afurika yo hagati no mu Burengerazuba.Kuva muri Gicurasi 2022, indwara ya monkeypox yibasiwe n’imigabane myinshi yarakomeje mu turere iyi ndwara itarakwirakwira, harimo Uburayi na Amerika, aho usanga umubare munini w’abantu bagaragara ku bagabo baryamana n’abagabo.Iki cyorezo cyatumye Ishami ry'Umuryango w'Abibumbye ryita ku Buzima hamwe na Minisiteri y’ubuzima n’Amerika ishinzwe ubuzima muri Amerika gutangaza ko byihutirwa ubuzima rusange.Kuva ku ya 1 Mutarama 2022 kugeza ku ya 5 Ukwakira 2022, OMS yatangaje ko abantu 68,900 bemeje ko hapfuye abantu 25 bapfa mu bihugu 106, intara n'intara.
Ishami ry'Umuryango w'Abibumbye ryita ku Buzima rivuga ko izo ndwara zagaragaye mu rwego rwo kwandura isi ikomeje guterwa ahanini na virusi ya mondeypox ya Clade IIb.Bivugwa ko icyiciro cya mbere gitera indwara zikomeye n’impfu nyinshi, cyane cyane ku bana, kuruta icyiciro cya IIa n’icyiciro cya IIb, kandi ni yo nyirabayazana w’ubwandu muri Repubulika Iharanira Demokarasi ya Kongo.Kuva ku ya 1 Mutarama 2022 kugeza ku ya 21 Nzeri 2022, Ikigo Nyafurika gishinzwe kurwanya no gukumira indwara (Afurika CDC) cyatangaje ko 3,326 banduye inkende (165 zemejwe; 3,161 bakekwaho) n’impfu 120.
Abantu barashobora kwanduza monkeypox binyuze mu guhura ninyamaswa zanduye nk'imbeba, inyamaswa zo mu bwoko bwa primates, cyangwa abantu.Virusi irashobora kwanduza abantu binyuze muburyo butaziguye no gukomeretsa uruhu, amazi yumubiri hamwe nigitonyanga cyo mu kirere, harimo guhuza ibitsina no guhuza ibitsina, ndetse no guhura mu buryo butaziguye n’imyenda yanduye cyangwa ibitanda.Monkeypox irashobora gutera ibimenyetso bisa n'ibicurane no kubabaza uruhu.Ingorane zirashobora kuba zirimo umwuma, kwandura bagiteri, umusonga, gutwika ubwonko, sepsis, kwandura amaso, no gupfa.
Ikigeragezo kizitabirwa n'abantu bakuru bagera kuri 450 hamwe n'abana bafite laboratoire yanduye ya monkeypox ipima byibura kg 3.Abagore batwite nabo bemerewe.Abakorerabushake bazahabwa inshingano zo gufata tecovirimat cyangwa capsules ya capboles mu kanwa kabiri kumunsi iminsi 14 kumunsi ikabije bitewe nuburemere bwabitabiriye.Ubushakashatsi bwari impumyi ebyiri, abitabiriye n'abashakashatsi ntibamenye uwakira tecovirimat cyangwa umwanya wabo.
Abitabiriye amahugurwa bose bazaguma mu bitaro byibuze iminsi 14 aho bazahabwa ubufasha bufasha.Abaganga b'iperereza bazahora bakurikirana uko abitabiriye amavuriro bameze mu bushakashatsi kandi bazasaba abitabiriye amahugurwa gutanga urugero rw'amaraso, kuvura umuhogo, n'ibikomere by'uruhu kugira ngo basuzume laboratoire.Intego nyamukuru yubushakashatsi kwari ukugereranya igihe ntarengwa no gukira ibikomere byuruhu kubarwayi bavuwe na tecovirimat na placebo.Abashakashatsi bazakusanya kandi amakuru ku ntego nyinshi z’icyiciro cya kabiri, harimo kugereranya uburyo abahugurwa bapimye vuba virusi ya monkeypox mu maraso yabo, ubukana muri rusange n’igihe cy’indwara, n’impfu ziri hagati y’amatsinda.
Abitabiriye amahugurwa basohotse mu bitaro nyuma yuko ibikomere byose bimaze gukonja cyangwa kubisiba kandi bakipimisha virusi ya monkeypox mu maraso yabo iminsi ibiri ikurikiranye.Bazubahirizwa byibuze iminsi 28 kandi bazasabwa gutaha muminsi 58 kugirango basure ubushakashatsi kubushake bwo kwisuzumisha kwa kliniki na laboratoire.Komite yigenga ishinzwe gukurikirana no kugenzura umutekano izagenzura umutekano w’abitabira mugihe cyo kwiga.
Ubushakashatsi bwari buyobowe n’umushakashatsi wungirije Jean-Jacques Muyembe-Tamfum, Umuyobozi mukuru wa INRB akaba na Porofeseri wa Microbiology, ishami ry’ubuvuzi, kaminuza ya Kinshasa, Gombe, Kinshasa;Placid Mbala, MD, Umuyobozi wa gahunda ya PALM, Umuyobozi w'ishami rya INRB Epidemiologiya na Laboratoire ya Pathogen.
Dr. Muyembe-Tamfum yagize ati: "Nishimiye ko monkeypox itakiri indwara ititaweho kandi ko bidatinze, kubera ubu bushakashatsi, tuzashobora kwerekana ko hari uburyo bunoze bwo kuvura iyi ndwara."
Kubindi bisobanuro, sura Clinicaltrials.gov hanyuma ushakishe ID NCT05559099.Gahunda yikizamini izaterwa nigipimo cyo kwiyandikisha.Urubanza rwa TPIXX rushyigikiwe na NIAID rurakomeje muri Amerika.Ushaka kumenya amakuru yerekeye ibigeragezo byo muri Amerika, sura urubuga rwa SIDA Clinical Trials Group (ACTG) hanyuma ushakishe TPOXX cyangwa wige A5418.
PALM ni amagambo ahinnye ya “Pamoja Tulinde Maisha”, interuro y'Igiswahiri isobanura “kurokora ubuzima hamwe”.NIAID yashyizeho ubufatanye bw’ubushakashatsi bw’ubuvuzi bwa PALM na Minisiteri y’ubuzima ya DRC mu rwego rwo guhangana n’icyorezo cya Ebola 2018 mu burasirazuba bwa DRC.Ubufatanye burakomeje nka gahunda y’ubushakashatsi bw’amavuriro menshi agizwe na NIAID, ishami ry’ubuzima rya DRC, abafatanyabikorwa ba INRB na INRB.Ubushakashatsi bwa mbere bwa PALM ni igeragezwa ryateganijwe ku buryo butandukanye bwo kuvura indwara ya virusi ya Ebola yashyigikiye kwemeza mAb114 yakozwe na NIAID (Ebanga) na REGN-EB3 (Inmazeb, yakozwe na Regeneron).
NIAID ikora kandi ishyigikira ubushakashatsi muri NIH, muri Amerika, ndetse no ku isi hose kugira ngo yumve ibitera indwara zanduza n’ubudahangarwa kandi zitezimbere uburyo bwiza bwo gukumira, gusuzuma, no kuvura izo ndwara.Itangaza makuru, ibinyamakuru, nibindi bikoresho bijyanye na NIAID birahari kurubuga rwa NIAID.
Ibyerekeye Ikigo cy’Ubuzima (NIH): Ikigo cy’igihugu cy’ubuzima (NIH) ni ikigo cy’ubushakashatsi cy’ubuvuzi muri Amerika cy’ibigo n’ibigo 27 kandi kiri mu ishami ry’ubuzima muri Amerika ryita ku buzima.NIH nicyo kigo cyibanze cya federasiyo ikora kandi igashyigikira ubushakashatsi bwubuvuzi bwibanze, bw’ubuvuzi, n’ubuhinduzi, bukora iperereza ku mpamvu zitera, kuvura, no kuvura indwara zisanzwe kandi zidasanzwe.Ukeneye ibisobanuro birambuye kuri NIH na gahunda zayo, sura kuri www.nih.gov.
Igihe cyo kohereza: Ukwakira-14-2022
